High dose Dexmedetomidine and Ketamine for Managing Difficult Pediatric Airways

High dose Dexmedetomidine and Ketamine for Managing Difficult Pediatric Airways

Dexmedetomidine is a useful drug to provide sedation and maintain spontaneous ventilation. Its use in pediatrics has increased over the last decade. Despite its utility as a cooperative sedative during difficult airway management in the adult population, this use in pediatrics is often not possible. As a result we present 3 cases of difficult pediatric airways that were secured using high dose ...

High dose dexmedetomidine as the sole sedative for pediatric MRI.

OBJECTIVE This large-scale retrospective review evaluates the sedation profile of dexmedetomidine. AIM To determine the hemodynamic responses, efficacy and adverse events associated with the use of high dose dexmedetomidine as the sole sedative for magnetic resonance imaging (MRI) studies. BACKGROUND Dexmedetomidine has been used at our institution since 2005 to provide sedation for pediatr...

Pediatric premedication: a double-blind randomized trial of dexmedetomidine or ketamine alone versus a combination of dexmedetomidine and ketamine

BACKGROUND Preoperative anxiety is common in pediatric patients. When dexmedetomidine is used alone for sedation as premedication, children tend to awaken when separated from their parents, and body movements occur during invasive procedures. We tested the hypothesis that the combination of dexmedetomidine and ketamine may be a useful premedication to alleviate preoperative anxiety and improve ...

Dexmedetomidine and low-dose ketamine provide adequate sedation for awake fibreoptic intubation.

PURPOSE We report the use of the alpha2 agonist, dexmedetomidine, with low-dose ketamine as a safe and effective treatment strategy to provide adequate comfort and sedation for a patient who fulfilled criteria of a difficult airway and required awake fibreoptic intubation (AFOI). CLINICAL FEATURES A 52-yr-old male with prostate cancer presented for radical prostatectomy. He reported several f...

Induction of Anesthesia with Dexmedetomidine and Sevoflurane for a Pediatric Difficult Airway